Effects of Di

Abstract The effects of the peroxisome proliferators di-isononyl phthalate (DINP) and di-2-ethylhexyl phthalate (DEHP) were evaluated in young adult male cynomolgus monkeys after 14 days of treatment with emphasis on detecting hepatic and other effects seen in rats and mice after treatment with high doses of phthalates

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Federal Register :: Di

DIDP is a phthalate used as a plasticizer to impart flexibility to polyvinyl chloride (PVC) in consumer commercial and industrial adhesives sealants lubricants greases and paints and coatings There are two commercial products that the manufacturer submitted for risk evaluation under the name DIDP

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DINP plasticizer

Jayflex™ DINP plasticizer is the largest-volume general-purpose high-molecular-weight plasticizer for PVC providing the opportunity for cost savings with a good balance of properties As shown below it is an excellent substitute for Di (2-ethylhexyl) phthalate (DOP) in most flexible PVC applications

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Jayflex™ DIDP (0 12% TCA)

Jayflex™ DIDP (0 12% TCA) by ExxonMobil Chemical is a general-purpose high-molecular-weight plasticizer It offers higher permanency for better resistance to aging increasing product life lower density and efficiency and increased PVC compound electrical resistivity for better insulation properties compared to DOP it provides low fogging for reduced car interior emissions sustained

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US California adds another Phthalate to the Proposition 65

Manufacturers whose products contain DINP and are sold in California should start assessing their products against Proposition 65 requirements If exposure is an issue decide whether to reformulate or to provide a clear and reasonable Proposition 65 warning which will take effect on 20 December 2014 one year after DINP is formally added to the Proposition 65 list

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Determining High

DiNP and DiDP using electron impact ion-ization (performed on a single quadrupole instrument) is shown in Figure 1 A com-plex cluster of DiNP and DiDP isomers is observed The spectrum taken at 25 6 min corresponding to the most abundant DiDP isomer is given in Figure 2 The molecular ion at m/z = 446 (C 28 H 46 O 4) cannot be detected

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Update of the risk assessment of di‐butylphthalate (DBP

based on the dataset used by European Chemicals Agency's Risk assessment committee (ECHA RAC) for its opinion of 2017 (DBP BBP DEHP di-isobutyl phthalate (DIBP)) In an updated mandate (May 2018 corrected in May 2019) EFSA was then requested to also include DINP and DIDP into the

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DIDP (di

en (13) The French authorities adopted on 5 July 1999 a measure suspending the marketing production import and export and ordering a withdrawal of certain toys and childcare articles intended for placing in the mouth by children under 36 months in soft PVC containing DINP DIDP DEHP DBP DNOP and BBP they have in addition notified the Commission within the framework of Directive 98/34/EC

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Ortho

High molecular weight (HMW) or high ortho-phthalates include those with 7-13 Carbon atoms in their chemical backbone which gives them increased permanency and durability The most common types of high ortho-phthalates include DINP DIDP DPHP DIUP and DTDP High ortho-phthalates represent just over 50% of the European plasticisers market

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BBP DINP DIDP or DNOP

BBP DINP DIDP or DNOP ISOFlex Packaging does not expect to find any phthalates in our films other than trace quantities that might be in the environment Because we do not add phthalates to our films or have any indication that any of these materials might be

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Hallstar Phthalate Alternatives Comparison in Medium ACN

used in place of phthalate esters Initially di-2-ethylhexyl phthalate (DEHP DOP) came under attack several years ago when it was classified as a potential carcinogen The natural progression for most compounders was to adopt di-isononyl phthalate (DINP) and di-isodecyl phthalate (DIDP) Now phthalates as a whole are coming under attack

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Selecting Adequate Exposure Biomarkers of Diisononyl and

Phthalates are high-production-volume chemicals Some phthalates are used as solvents and additives and are often found in personal care products such as cosmetics lotions and perfumes and in the coatings of some medications (David et al 2001 Koch and Calafat 2009 Schettler 2006) Others including diisononyl phthalate (DINP) and diisodecyl phthalate (DIDP) are used primarily as

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Intercide™ DBF

Intercide ™ DBF-10 DIDP contains 72 5% DIDP Therefore when using this product in a compound the appropriate adjustment of plasticizer in the formulation must be made For example if 2% of Intercide ™ DBF-10 DIDP is used then a 1 45% reduction of plasticizer is required to maintain equivalent plasticity

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BBP DINP DIDP or DNOP

BBP DINP DIDP or DNOP ISOFlex Packaging does not expect to find any phthalates in our films other than trace quantities that might be in the environment Because we do not add phthalates to our films or have any indication that any of these materials might be

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Weight of Evidence Indicates That DINP Should Not Be

2 The report concludes that 'a risk from the mouthing of toys and childcare articles with DINP cannot be excluded if the existing restriction were lifted' However based on the risk assessment in the report ECHA also concludes that no further risk management measures are needed to reduce the exposure of children and adults to DINP

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US CALIFORNIA INCORPORATES DIISONONYL PHTHALATE (DINP

4 DIDP Diisodecyl phthalate 5 DINP Diisononyl phthalate 6 DNOP Di-n-octyl phthalate 7 DnHP Di-n-hexyl phthalate 8 CPSIA Consumer Product Safety Improvement Act of 2008 9 CCPSA Canada Consumer Product Safety Act 2 Public Law 110–314-110th Congress

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Di

DIDP belongs to a family of chemicals called phthalates which are added to some plastics to make them flexible DIDP is used in various types of plastic consumer products including: Some polyvinyl chloride (PVC vinyl) tubing materials used in automobile interiors garden hoses raincoats binders storage cases tile flooring shower curtains and bath mats

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SGS

TABLE 2 OVERVIEW TABLE MAXIMUM SPECIFIC MIGRATION LIMITS (SML) OF MATERIALS IN FOOD CONTACT AS INDICATED BY THE BELGIAN FOOD AGENCY PHTHALATE SML (IN MG PER KG FOOD SIMULANT) DEHP 1 5 BBP 30 DBP 0 3 DINP 9 DIDP Sum of DIDP + DINP + DINCH + DEHP + DBP + BBP 60 Taiwan DOH has publicized a standard method that is applicable for the

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Technical report of the public consultation on the 'Draft

1B but not the other two investigated phthalates (DINP DIDP) Despite not having been mentioned explicitly in the mandate of May 2018 the CEP Panel took into consideration the ECHA opinion on DINP (2018) when preparing the draft opinion that has undergone public consultation International organisation 5 NGO 2

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