Naturally occurring phenols

In biochemistry naturally occurring phenols refers to phenol functional group that is found in natural products Phenolic compounds are produced by plants and microorganisms Organisms sometimes synthesize phenolic compounds in response to ecological pressures such as pathogen and insect attack UV radiation and wounding As they are present in food consumed in human diets and in plants used

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Momordica Charantia Lectin a Type II Ribosome

The incidence of nasopharyngeal carcinoma (NPC) remains high in endemic regions including southern China northern Africa and North America One of the promising therapeutic approaches on NPC is drug screening from natural products such as components from traditional Chinese medicine In this study the antitumor activity of Momordica charantia lectin (MCL) a type II ribosome inactivating

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Leucine operon leader — Wikipedia Republished // WIKI 2

RNA type Cis-reg leader: Domain(s) Bacteria: SO: 0000233: PDB structures: PDBe: The Leucine operon leader is an RNA element found upstream of the first gene in the Leucine biosynthetic operon The leader sequence can assume two different secondary structures known as the terminator and the anti-terminator structure The leader also codes for very short peptide sequence that is rich in leucine

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Adenovirus Type 37 Uses Sialic Acid as a Cellular Receptor

Ad5 or Ad37 virions were diluted in BB and added to the cells at concentrations corresponding to 5 000 fluorescent focus units (FFU) per cell type and sample Hence the virion dilutions were adjusted so that 100 FFU/viewing field were obtained in the control (nontreated cells) The cells were then incubated on ice permitting attachment of virions but not internalization After 1 h unbound

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Medical biochemistry

Medical biochemistry 1 LECTURE NOTES For Health Science Students Medical Biochemistry Solomon Adugna Lakshmi Ahuja Mekonnen Alemu Tsehayneh Kelemu Henok Tekola Belayhun Kibret Solomon Genet Gondar University Jimma University Debub University In collaboration with the Ethiopia Public Health Training Initiative The Carter Center the Ethiopia Ministry of Health and the Ethiopia

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A Family of Dual

Sernee et al show that metabolism of the Leishmania carbohydrate reserve mannogen is mediated by a single family of enzymes acquired by horizontal gene transfer The evolution of this pathway may have allowed these parasites to expand their host range and colonize intracellular niches in

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Polysaccharides functionalized by tryptophan derivatives

3-6-2010The present invention relates to novel polysaccharide derivatives predominantly comprising glycosidic bonds of (1 4) (1 3) and/or (1 2) type functionalized by at least one tryptophan derivative It also relates to processes for the synthesis thereof to their uses as pharmaceutical excipient and to the pharmaceutical compositions comprising them

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Nucleotide

Read Nucleotide-type chemical shift assignment of the encapsulated 40 kbp dsDNA in intact bacteriophage T7 by MAS solid-state NMR Journal of Biomolecular NMR on DeepDyve the largest online rental service for scholarly research with thousands of academic publications available at

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Investigation of post

The investigation of post-translational modifications (PTMs) plays an important role for the study of type 2 diabetes The importance of PTMs has been realized with the advancement of analytical techniques The challenging detection and analysis of post-translational modifications is eased by different enrichment methods and by high throughput mass spectrometry based proteomics studies

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New paradigms in adenosine receptor pharmacology

New paradigms in adenosine receptor pharmacology Recent paradigms include the following: (i) allosteric modulation the influence on ligand pharmacology observed upon the binding of a second ligand to a topographically distinct but conformationally linked binding site on the receptor macromolecule (ii) biased agonism ligand‐dependent stabilization of differential receptor conformations

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Therapeutic strategies for tau mediated neurodegeneration

Based on the amyloid hypothesis controlling β-amyloid protein (Aβ) accumulation is supposed to suppress downstream pathological events tau accumulation neurodegeneration and cognitive decline However in recent clinical trials Aβ removal or reducing Aβ production has shown limited efficacy Moreover while active immunisation with Aβ resulted in the clearance of Aβ it did not

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Chemical convergence between plants and insects

Despite the phylogenetic distance between plants and insects these two groups of organisms produce some secondary metabolites in common Identical structures belonging to chemical classes such as the simple monoterpenes and sesquiterpenes iridoid monoterpenes cyanogenic glycosides benzoic acid derivatives benzoquinones and naphthoquinones are sometimes found in both plants and insects

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Measuring Lactase Enzymatic Activity in the Teaching Lab

The glycosidic hydrolase lactase (EC 3 2 1 23/26) is an enzyme of central nutritional importance for mammals 3 The activity of lactase is highly conserved through evolution and derives from the beta-galactosidase family of enzymes — a family present from Escherichia coli through to Homo sapiens (Figure 1 PDB 1JZ8) 4

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Illustrate a glycosidic peptide and a phospho diester bond

(a) Glycosidic bond is formed normally between C-1 and C-4 of adjacent monosaccharide units (c) Phosphodiester bond is a strong covalent bond formed between phosphate and two adjacent sugar groups Such bonds form the sugar phosphate backbone of nucleic acids

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Quorum Sensing in Marine Microbial Environments

Quorum sensing (QS) is a form of chemical communication used by certain bacteria that regulates a wide range of biogeochemically important bacterial behaviors Although QS was first observed in a marine bacterium nearly four decades ago only in the past decade has there been a rise in interest in the role that QS plays in the ocean It has become clear that QS regulated by signals such as

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[Full text] Preparation characterization and potential

Hydrophobic particles easily penetrate into the tissues which is not the case for hydrophilic ones On the contrary nanoparticles that are hydrophilic even through coating with PEG or surfactants of nonionic type and additionally smaller than 100 nm will bypass the phagocytosis performed by macrophages Coating the prepared particles by

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The β

Lotus japonicus accumulates the hydroxynitrile glucosides lotaustralin linamarin and rhodiocyanosides A and D Upon tissue disruption the hydroxynitrile glucosides are bioactivated by hydrolysis by specific β -glucosidases A mixture of two hydroxynitrile glucoside-cleaving β -glucosidases was isolated from L japonicus leaves and identified by protein sequencing as LjBGD2 and LjBGD4

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Cellular Defenses against Superoxide and Hydrogen

This bond in turn is reduced upon reversible binding of the NADH-reducible flavoprotein AhpF This arrangement optimizes the rate of H 2 O 2 reduction rather than enzyme recycling That is fitting: Under physiological conditions each protein need not turn over very frequently but there is a premium on the rapidity with which each molecule of H 2 O 2 is consumed by the first half of the

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